Jual Diisopropylamine

Jual Diisopropylamine (DIPA) is a secondary amine compound widely used in various chemical industries. Known for its role as a base in organic synthesis, DIPA finds application across multiple sectors, including pharmaceuticals, agrochemicals, and rubber processing.

Table of Contents

Diisopropylamine: An Overview Jual Diisopropylamine

Chemical Formula: $C_{6} H_{15} N$
Molecular Weight: 101.19 g/mol
IUPAC Name: N-(1-methylethyl)-propan-2-amine

DIPA is a secondary amine, meaning it contains two organic groups attached to the nitrogen atom, specifically two isopropyl groups in this case. The nitrogen atom bonded to two carbon groups and one hydrogen atom gives DIPA its characteristic properties, such as moderate basicity and volatility.

Appearance: DIPA is a colorless liquid with a faint fish-like odor, typical of amines.
Boiling Point: Approximately 84-85°C
Melting Point: -61°C
Solubility: It is moderately soluble in water and more soluble in organic solvents like ethanol, ether, and acetone.
pKa Value: 11.0 (measured in water), indicating moderate basicity.
Density: 0.722 g/mL at 25°C.

Production and Synthesis

Jual Diisopropylamine can be synthesized through various methods, but one of the most common approaches is through the reaction of isopropylamine with isopropyl alcohol or by reacting isopropyl chloride with ammonia, then distilling the resulting mixture.

Another synthesis method involves:

Catalytic Hydrogenation: Starting from other nitrogen-containing precursors, the reduction of diisopropylketone with hydrogen gas in the presence of a catalyst (such as nickel) also yields DIPA.

Uses of Diisopropylamine

DIPA’s utility spans a variety of industries:

Organic Synthesis: Often used as a base in deprotonation reactions or as a catalyst. Its basicity, coupled with the steric hindrance from the isopropyl groups, makes DIPA a favored choice in organic reactions where strong bases are needed but unwanted side reactions must be minimized.
Pharmaceuticals: DIPA is often a key component in synthesizing pharmaceutical intermediates and active ingredients. It acts as a reagent in the production of many drugs, particularly in the creation of antihistamines, antidepressants, and antiviral drugs.
Agricultural Chemicals: Diisopropylamine is used in the synthesis of herbicides, pesticides, and fungicides. Compounds derived from DIPA include certain amine salts, which improve the effectiveness of herbicidal activity.
Rubber and Plastic Industries: As an accelerator in rubber processing, DIPA is added to improve the properties and processing of various rubber types, including natural and synthetic rubber. It enhances the curing process and helps control the rate of cross-linking, making the final rubber products more durable.
DIPA Salts: When reacted with strong acids, DIPA forms salts that are widely used in industry. For example, diisopropylamine hydrochloride is used in synthesis as an intermediate or to help control reaction rates.

Handling and Storage

Jual Diisopropylamine is highly flammable and should be handled with care. Due to its volatility and risk of forming explosive mixtures with air, it should be stored in well-ventilated areas, away from sources of ignition and heat.

Personal Protective Equipment (PPE): Standard PPE such as gloves, goggles, and protective clothing are recommended.
Storage Conditions: Store in cool, dry areas in containers with proper labels. Avoid prolonged exposure to air as it can lead to oxidation or degradation of the compound.
Handling Precautions: Given its tendency to form vapors, it should be used in areas with adequate ventilation, ideally in a fume hood in laboratory settings.

Health Hazards and Safety Measures Jual Diisopropylamine

Acute Exposure: Short-term exposure to DIPA can cause respiratory and skin irritation. The vapors may irritate the eyes, nose, and throat. In high concentrations, DIPA may lead to symptoms such as dizziness, headache, and nausea.

Chronic Exposure: Prolonged or repeated exposure can potentially damage the liver, kidneys, and nervous system.

First Aid Measures:

Inhalation: If inhaled, move the person to fresh air immediately and seek medical attention if symptoms persist.
Skin Contact: Rinse the affected area with plenty of water and remove any contaminated clothing.
Eye Contact: Flush the eyes with water for several minutes and seek medical help if irritation persists.
Ingestion: Do not induce vomiting. Rinse the mouth and seek immediate medical attention.

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Jual Diisopropylamine has a moderate environmental impact. If released into the environment, it can be harmful to aquatic life and may contribute to air pollution due to its volatility. DIPA’s disposal should follow local environmental regulations. It is typically neutralized and then safely disposed of by a licensed chemical waste management service.